Relationship: Acquired Immune Deficiency Syndrome and selenium

Evidence supporting the use of: Selenium
For the health condition: Acquired Immune Deficiency Syndrome

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Source of validity: Scientific
Rating (out of 5): 2

Selenium has been investigated for its potential role in supporting individuals with Acquired Immune Deficiency Syndrome (AIDS), primarily due to its function as an essential trace element involved in antioxidant defense systems and immune function. Several observational studies have found that people with HIV/AIDS often exhibit lower blood selenium levels compared to healthy controls, and lower selenium status has been associated with faster disease progression and increased mortality. Some randomized controlled trials (RCTs) have assessed selenium supplementation in HIV-positive individuals. For example, a 2007 RCT published in Archives of Internal Medicine found that selenium supplementation (200 μg/day) for 9 months helped reduce hospital admissions and improve CD4 cell counts in HIV-infected adults. Another RCT published in JAMA in 2013 found that selenium combined with multivitamins slowed HIV disease progression in pregnant women. However, other trials have shown more modest or non-significant effects, and the overall quality and consistency of evidence is limited.

Current scientific evidence suggests that selenium supplementation may have beneficial effects in some individuals with HIV/AIDS, particularly those with documented selenium deficiency. However, it is not considered a primary or standalone therapy for AIDS and should not replace antiretroviral treatment. Guidelines from major health organizations do not universally recommend routine selenium supplementation for all HIV/AIDS patients, but acknowledge that supplementation may be warranted in cases of deficiency. Overall, the scientific evidence supporting selenium use in AIDS is limited to modest, supportive roles, and more research is needed to clarify its clinical utility.

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Evidence supporting the use of: Selenium
For the health condition: Acquired Immune Deficiency Syndrome

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Evidence supporting the use of: SeleniumFor the health condition: Acquired Immune Deficiency Syndrome

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Synopsis

Other ingredients used for Acquired Immune Deficiency Syndrome

Other health conditions supported by selenium

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Evidence supporting the use of: Selenium
For the health condition: Acquired Immune Deficiency Syndrome