Evidence supporting the use of: Gymnemic acid
For the health condition: Addictions (sugar or refined carbohydrates)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Gymnemic acid, a primary active component of the plant Gymnema sylvestre, has garnered interest for its potential to support sugar and refined carbohydrate addiction, particularly by modulating taste perception and glucose absorption. Several studies have shown that gymnemic acids can temporarily suppress the ability to taste sweetness by blocking sweet receptors on the tongue. This effect can decrease the desire to consume sweet foods, which may be beneficial for individuals attempting to reduce their sugar intake. Animal studies and some small-scale human trials suggest that gymnemic acid may reduce the intake of sweet foods and potentially influence appetite regulation. For example, clinical trials have found that participants consuming gymnemic acid extracts experienced reduced desire for sugary foods and, in some cases, consumed fewer calories from sweets. Furthermore, gymnemic acid may interfere with intestinal glucose absorption, which could indirectly affect cravings by stabilizing blood sugar levels. However, the quality and scale of clinical evidence remain limited. Most studies are short-term, involve small numbers of participants, or are preclinical (animal or in vitro). While there is a plausible biological mechanism and some preliminary clinical support, robust, large-scale randomized controlled trials are lacking. Thus, while the use of gymnemic acid for sugar or refined carbohydrate addiction has some scientific basis, the evidence is still considered preliminary and not yet conclusive.

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