Evidence supporting the use of: DL-phenylalanine
For the health condition: Addictions (tobacco smoking or chewing)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 1

DL-Phenylalanine (DLPA) is sometimes used as a supplement to support addiction recovery, including tobacco use, based on its role as a precursor to neurotransmitters such as dopamine, norepinephrine, and endorphins. The theoretical basis is that boosting these neurotransmitters may help alleviate withdrawal symptoms and cravings, since addictions often disrupt reward pathways linked to dopamine and endorphin function.

However, evidence for DLPA in treating tobacco or other addictions is minimal and primarily extrapolated from biochemical theory. A handful of small or preliminary studies (mostly from the 1980s and 1990s) explored amino acid precursors for addiction, but robust clinical trials with DLPA specifically for tobacco cessation are lacking. Most reports are anecdotal or based on its use as an adjunct therapy in broader "amino acid therapy" protocols. Reviews and guidelines for smoking cessation do not include DLPA as an evidence-based option.

In summary, while the theoretical and preclinical rationale for using DL-phenylalanine exists, the clinical evidence is very weak. Its use is not standard medical practice, and it is not recommended as a primary or proven therapy for tobacco addiction.

More about DL-phenylalanine
More about Addictions (tobacco smoking or chewing)

Products containing DL-phenylalanine

We currently have no products on Vitabase that contain this ingredient.