Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Scrophularia root, commonly known as figwort root, is primarily used in Traditional Chinese Medicine (TCM) and other traditional herbal systems to treat conditions involving swelling, inflammation, and glandular disorders, including adenitis (inflammation of the glands, particularly lymph nodes). Traditionally, Scrophularia ningpoensis (Xuan Shen) is considered to have "heat-clearing" and "detoxifying" properties, which are believed to help reduce swelling and dissipate nodules. Classic TCM texts mention its application in cases of scrofula (tuberculous lymphadenitis) and other manifestations of glandular inflammation.

There is limited scientific research specifically evaluating Scrophularia root for adenitis. While some phytochemical studies have identified iridoid glycosides, phenolic acids, and other compounds with anti-inflammatory and immunomodulatory properties, direct clinical evidence for efficacy in adenitis is lacking. Most modern investigations focus on the root's general anti-inflammatory effects or its use in broader inflammatory conditions, not specifically on glandular inflammation or adenitis in human subjects. The traditional use is strong and well-documented, but the scientific validation remains preliminary and indirect.

In summary, the use of Scrophularia root for adenitis is justified primarily by traditional herbal medicine practices, with a modest (2/5) evidence rating due to a lack of robust clinical trials or direct scientific studies on this specific indication.

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