Eurycoma longifolia, also known as Tongkat Ali or Malaysian ginseng, has a long history of traditional use in Southeast Asian herbal medicine. It is primarily employed as an adaptogen, aphrodisiac, and general tonic to combat fatigue, improve libido, and enhance physical endurance. Its reputation for "restoring energy" and "vitality" has led to the belief that it supports the adrenal cortex, the part of the adrenal glands responsible for producing stress hormones like cortisol.

However, scientific research specifically linking Eurycoma longifolia to direct support of the adrenal cortex is limited. The majority of modern studies have focused on its potential to increase testosterone, improve mood, and reduce stress, rather than directly measuring adrenal cortex function or hormone output. Some studies indicate that it may reduce cortisol levels and improve stress response, which could suggest indirect support for adrenal health, but these findings are preliminary and not conclusive.

In summary, the use of Eurycoma longifolia for adrenal cortex support is justified primarily by traditional use and anecdotal reports, rather than robust scientific validation. More targeted research is required to confirm its effects on adrenal cortex physiology.