Evidence supporting the use of: Ox
For the body system: Adrenal Cortex

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Ox adrenal cortex (bovine adrenal gland extract) has been used in traditional and alternative medicine to support adrenal function, particularly for conditions believed to involve "adrenal fatigue" or low adrenal output. The rationale for its use stems from the idea that consuming animal glandular tissues may support the corresponding human glands—a concept popularized in the early 20th century before the advent of modern endocrinology and synthetic hormone replacement.

However, there is minimal scientific evidence to support the efficacy of bovine adrenal cortex preparations for supporting human adrenal function. Most claims are based on historical practices and anecdotal reports rather than controlled clinical trials. Furthermore, regulatory agencies such as the FDA have not approved adrenal glandular supplements for the treatment of any adrenal disorders.

Some practitioners in the field of naturopathy and alternative medicine continue to recommend these supplements, but mainstream medicine does not recognize "adrenal fatigue" as a diagnosable condition, and there is a lack of robust scientific validation for these products. Therefore, the use of ox adrenal cortex for adrenal support is primarily justified by tradition rather than scientific evidence.

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