Evidence supporting the use of: Vitamin B5 (Calcium Pantethine)
For the body system: Adrenal Cortex

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitamin B5, also known as pantothenic acid (and its derivative, calcium pantethine), is traditionally considered important for adrenal health. This belief originates from early animal studies and nutritional observations in the mid-20th century. Some early research showed that severe pantothenic acid deficiency in animals led to impaired adrenal function and decreased synthesis of adrenal hormones, such as cortisol. As a result, pantothenic acid became associated with the support of the adrenal cortex, which produces stress hormones. However, robust clinical evidence in humans is lacking. While pantothenic acid is indeed essential for coenzyme A synthesis and overall metabolic function, including the biosynthesis of steroid hormones in the adrenal cortex, there is minimal direct human research indicating that supplementation with vitamin B5 or calcium pantethine specifically enhances adrenal function or stress resilience in individuals with adequate dietary intake. Most modern uses in adrenal support formulas are based on tradition and extrapolation from animal studies rather than rigorous clinical trials. In summary, the use of vitamin B5 (calcium pantethine) for supporting the adrenal cortex is primarily justified by historical and traditional rationale, with limited scientific validation in humans. It remains an essential nutrient, but its role as a targeted adrenal support supplement is not strongly supported by current clinical evidence.

More about Vitamin B5 (Calcium Pantethine)
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Other body systems supported by Vitamin B5 (Calcium Pantethine)

Adrenal Cortex
Adrenal Glands
Circulatory System
Glandular System
Heart

Products containing Vitamin B5 (Calcium Pantethine)

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