Evidence supporting the use of: Vitamin B5 (calcium pantothenate)
For the body system: Adrenal Cortex
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Vitamin B5 (calcium pantothenate) is traditionally used to support the adrenal cortex and overall adrenal function, largely due to its role as a precursor of coenzyme A, which is involved in numerous metabolic pathways, including the synthesis of adrenal hormones such as cortisol. Historical use in naturopathic and alternative medicine circles often cites B5 as an "anti-stress" vitamin, suggesting that it supports adrenal health during periods of physical or psychological stress. However, scientific evidence specifically linking vitamin B5 supplementation to improved adrenal cortex function or to the prevention or treatment of adrenal fatigue in humans is limited and primarily anecdotal. Some animal studies from the mid-20th century suggested that B5 deficiency could impair adrenal function, but robust clinical trials in humans are lacking. Current scientific consensus does recognize B5 as essential for general metabolism and hormone synthesis, but not specifically for targeted adrenal support beyond normal dietary requirements. Therefore, the use of vitamin B5 for adrenal cortex support is better characterized as traditional rather than scientifically validated.
More about Vitamin B5 (calcium pantothenate)
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AcetylcholineAdrenal Cortex
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