Evidence supporting the use of: Eleutheroside
For the health condition: Adrenal Fatigue

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Eleutheroside refers to a group of active compounds found in Eleutherococcus senticosus (Siberian ginseng), an herb traditionally used in Russian and Chinese medicine. Historically, Siberian ginseng has been used as an "adaptogen," a term for substances believed to help the body resist physical, chemical, and biological stressors. This traditional use includes supporting energy, endurance, and resilience to stress, which has led to its popular application in “adrenal fatigue”—a non-medical term sometimes used to describe symptoms of chronic stress and fatigue. However, “adrenal fatigue” is not recognized as a legitimate medical diagnosis by mainstream medicine, and there is limited clinical research specifically connecting eleutherosides or Siberian ginseng to this condition. Some studies suggest adaptogenic herbs may help modulate the stress response and reduce fatigue, but evidence is generally weak, inconsistent, or not directly linked to adrenal function. The use of eleutherosides for “adrenal fatigue” persists primarily due to tradition and anecdotal reports, rather than robust scientific validation. Overall, the evidence supporting its use for this specific condition is limited and should be viewed with caution. Consult a healthcare provider for evidence-based approaches to fatigue and stress.

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Products containing Eleutheroside

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