Evidence supporting the use of: San-Qi Ginseng
For the health condition: Adrenal Fatigue

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

San-Qi Ginseng (Panax notoginseng) is primarily used in Traditional Chinese Medicine (TCM), where it is valued for its ability to "invigorate blood," "stop bleeding," and "reduce swelling and pain." While not traditionally described in terms of “adrenal fatigue,” practitioners of TCM may use San-Qi Ginseng in formulas that address symptoms overlapping with what is described as adrenal fatigue in alternative medicine—such as fatigue, weakness, and stress. However, the concept of "adrenal fatigue" itself is not recognized in mainstream medicine and does not have a direct analog in TCM.

Scientific evidence specifically linking San-Qi Ginseng to improvement in adrenal function or the treatment of so-called adrenal fatigue is lacking. Some studies have shown that Panax notoginseng and its saponins may have adaptogenic, anti-inflammatory, and anti-fatigue effects in animal models, but these effects have not been robustly demonstrated in humans, nor directly tied to adrenal health.

Thus, the use of San-Qi Ginseng for adrenal fatigue is justified more by traditional use patterns and anecdotal reports than by scientific validation. The evidence supporting its efficacy for this purpose is low, meriting a rating of 2 out of 5, primarily because of traditional precedent rather than rigorous clinical evidence.

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