Evidence supporting the use of: Blend (herb/botanical)
For the body system: Adrenal Glands

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Herbal blends designed to support the adrenal glands often include botanicals such as ashwagandha, rhodiola, licorice root, and holy basil. The use of these herbs for "adrenal support" is primarily rooted in traditional systems of medicine, such as Ayurveda and Traditional Chinese Medicine, where they are classified as adaptogens—substances believed to help the body resist stressors of all kinds. For example, ashwagandha (Withania somnifera) has been used for centuries to increase energy, improve resilience to stress, and promote overall vitality. Licorice root (Glycyrrhiza glabra) has a history of use for supporting energy and combating fatigue, which are symptoms sometimes associated with so-called "adrenal fatigue." Rhodiola (Rhodiola rosea) and holy basil (Ocimum sanctum) also have a long-standing tradition of use for enhancing the body's adaptation to stress.

While there is some preliminary scientific evidence suggesting these herbs may help modulate the body's stress response, direct evidence for their effect on adrenal gland function in humans is limited. Most research focuses on their impact on perceived stress, fatigue, and cortisol levels. The concept of "adrenal fatigue" itself is not recognized in mainstream medicine, and most evidence for these blends relies on traditional use and small-scale studies rather than large, rigorous clinical trials. Thus, while tradition supports their use for stress and vitality, scientific validation for direct adrenal support remains limited.

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