The use of "Botanical Blend" to support adrenal gland health is primarily justified by traditional practices rather than strong scientific evidence. "Botanical Blend" is a general term often referring to a mixture of plant extracts—common examples for adrenal support include ashwagandha, licorice root, rhodiola, and ginseng. These herbs have been used in traditional medicine systems such as Ayurveda, Traditional Chinese Medicine, and European herbalism to address symptoms associated with stress, fatigue, and adrenal function. For instance, ashwagandha has been utilized for its adaptogenic properties, believed to help the body adapt to stress. Licorice root has historically been used for its purported effects on cortisol metabolism and adrenal insufficiency. However, while there are a few small clinical studies and animal research suggesting possible beneficial effects of some individual herbs (such as ashwagandha and rhodiola) on stress response and fatigue, comprehensive scientific validation for the efficacy of multi-herb "botanical blends" specifically for adrenal support is lacking. Most of the evidence remains anecdotal or based on traditional usage, with a need for more rigorous, large-scale human trials to confirm safety and effectiveness. Thus, the rationale for using botanical blends for the adrenal system is mostly rooted in historical and traditional use rather than robust scientific validation.