Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Bovine (unspecified) glandular extracts, including those derived from adrenal glands, have a long history of use in traditional and alternative medicine, particularly within naturopathic and early 20th-century holistic practices. The underlying belief is that consuming animal organ tissues can support the corresponding organ system in humans—a concept sometimes called "like supports like." In the case of adrenal supplements, practitioners historically used bovine adrenal extracts to help people with symptoms of “adrenal fatigue,” low energy, and stress. However, this practice emerged before the advent of modern endocrinology and lacks support from rigorous scientific studies.

Modern clinical research provides little evidence that orally ingested bovine adrenal tissue exerts any measurable effect on human adrenal function or hormone levels. Most adrenal hormones (such as cortisol) present in supplements are broken down during digestion and do not survive to reach the bloodstream intact. Regulatory bodies like the FDA have not approved bovine adrenal extracts for treating any medical condition. Nevertheless, the tradition persists, primarily within alternative health circles, based on anecdotal reports and historical precedent rather than validated clinical outcomes.

In summary, while the use of bovine adrenal extracts to support adrenal gland health is grounded in tradition, the scientific evidence supporting their efficacy is minimal to nonexistent.

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