Evidence supporting the use of: Bupleurum
For the body system: Adrenal Glands

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Bupleurum, known in traditional Chinese medicine (TCM) as Chai Hu, has been used for centuries primarily to support liver health and to help the body adapt to stress. Its use for "adrenal support" is a modern interpretation, largely rooted in the herb's traditional role as an adaptogen—an agent thought to help the body cope with stressors. In TCM, Bupleurum is often included in formulas intended to "soothe the Liver" and "harmonize" bodily functions, which some modern practitioners associate with adrenal function, given the adrenal glands' role in stress response. However, there is no direct mention of adrenal glands in classical texts, as the concept did not exist historically within TCM frameworks.

Scientific studies on Bupleurum primarily focus on its anti-inflammatory, hepatoprotective, and immunomodulatory effects, with little direct evidence relating to adrenal gland health or function. While some animal studies suggest Bupleurum extracts may modulate stress responses, robust clinical trials in humans specifically linking Bupleurum to improved adrenal function are lacking. Therefore, its use for adrenal support is justified by traditional herbal practices and indirect associations, rather than by strong scientific evidence. The rating reflects this reliance on tradition over direct scientific validation.

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