Evidence supporting the use of: Chinese Thoroughwax
For the body system: Adrenal Glands

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Chinese Thoroughwax (Bupleurum chinense), known as "Chai Hu" in Traditional Chinese Medicine (TCM), has a long history of use primarily for its effects on the liver and as a harmonizer of bodily systems. In traditional practice, it is sometimes included in formulas intended to address symptoms that, in Western herbal frameworks, are attributed to adrenal fatigue or stress-related disorders. However, thoroughwax has not been classically described in TCM texts as supporting the adrenal glands specifically, since adrenal glands are a Western anatomical concept. Its traditional use is more aligned with harmonizing the liver qi, supporting the body's response to stress, and promoting overall vitality.

Scientific evidence directly linking Chinese Thoroughwax to adrenal support is limited. Some in vitro and animal studies suggest that Bupleurum and its constituents (notably saikosaponins) may exert anti-inflammatory and adaptogenic effects, which are sometimes extrapolated as supporting the body's stress response, a function often attributed to the adrenal glands in Western herbalism. However, robust clinical trials demonstrating direct benefit to human adrenal gland function are lacking.

In summary, the use of Chinese Thoroughwax for "adrenal support" is primarily justified by traditional use and indirect evidence, rather than direct scientific validation or a strong historical precedent explicitly linking it to the adrenal glands.

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