Evidence supporting the use of: Cynanchum wilfordii
For the body system: Adrenal Glands

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Cynanchum wilfordii is primarily used in traditional East Asian medicine, particularly in Korea and China, where it is known as "baekshuoh" or "baeksuo." Its use is based on historical and ethnobotanical practices rather than robust scientific evidence. In traditional medicine, Cynanchum wilfordii has been used as a tonic to promote general vitality, which may be interpreted broadly as support for energy and resilience, sometimes loosely associated with adrenal health or stress adaptation. However, there is a lack of direct traditional reference to the "adrenal glands" as understood in modern physiology; rather, the plant is used to address symptoms like fatigue and weakness, which some modern supplement marketers extrapolate to adrenal support.

Scientific research on Cynanchum wilfordii has focused largely on its potential effects on lipid metabolism, menopause symptoms, and antioxidant properties. There are no well-designed clinical studies directly linking Cynanchum wilfordii to adrenal gland function or to specific effects on adrenal hormones such as cortisol. Most references to adrenal support in the context of Cynanchum wilfordii are anecdotal or based on extrapolation from its general tonic properties in traditional systems. Therefore, its use for supporting the adrenal glands is justified by tradition rather than by scientific validation, and the strength of evidence is weak.

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