Evidence supporting the use of: Eleuthero Root
For the body system: Adrenal Glands

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Eleuthero root (Eleutherococcus senticosus), also known as Siberian ginseng, has a long history of use in traditional herbal medicine, particularly in Russia and China. Traditionally, it has been used as an "adaptogen"—a substance believed to help the body resist stressors, support energy levels, and maintain homeostasis, including supporting the function of the adrenal glands. The rationale is that adaptogens may help the body cope with physical, emotional, and environmental stress, thereby indirectly supporting the adrenal glands, which play a key role in the stress response via hormone production (notably cortisol).

Scientific studies on eleuthero have primarily focused on its potential to improve physical endurance, reduce fatigue, and enhance overall resistance to stress in both animal and human models. Some small clinical trials and animal studies suggest mild benefits in stress adaptation, but direct evidence for eleuthero’s ability to support adrenal gland health (specifically structure or hormone production) is limited and indirect. Most evidence available is not robust or specific to adrenal function, but rather to general stress response and fatigue reduction.

In summary, while eleuthero has a well-established traditional use as an adaptogen thought to support adrenal health, scientific evidence is limited and not definitive. Its use in supporting the adrenal glands is therefore justified primarily by tradition, with moderate but not strong supporting evidence from scientific studies.

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