Evidence supporting the use of: Eleutherococcus senticosus
For the body system: Adrenal Glands

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Eleutherococcus senticosus, commonly known as Siberian ginseng, has a long history of use in traditional medicine, particularly in Russia and China, as an "adaptogen"—a substance believed to help the body adapt to stress. The traditional rationale for its use to support the adrenal glands is rooted in the concept that adaptogens enhance the body's resistance to stress and help maintain homeostasis, which includes support for adrenal function given the adrenal glands' role in stress hormone production. Historical texts and ethnobotanical records describe its use for increasing stamina, reducing fatigue, and improving overall vitality during periods of physical or mental stress.

Scientific studies have explored Eleutherococcus senticosus for its adaptogenic effects, with some animal and human studies suggesting it may help modulate the stress response, reduce fatigue, and improve mental performance. However, direct evidence showing a specific benefit to adrenal gland structure or function in humans is limited. Most research focuses on general stress resilience, immune modulation, and fatigue reduction, not direct adrenal support. Thus, while there is a moderate traditional basis and some indirect scientific support for its adaptogenic effects, the claim that it directly supports adrenal glands is primarily rooted in traditional use.

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