Evidence supporting the use of: Eleutheroside
For the body system: Adrenal Glands

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Table of Contents

Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Eleutheroside refers to a group of active compounds primarily found in Eleutherococcus senticosus, commonly known as Siberian ginseng. Its use for supporting the adrenal glands is rooted in traditional herbal medicine, particularly in Russia and parts of Asia, where it has a long history as an adaptogen—a substance believed to help the body resist physical, chemical, and biological stress. Traditional use has often focused on addressing symptoms associated with "adrenal fatigue" or enhancing resilience to stress, both of which are linked to adrenal gland function in popular and naturopathic medicine frameworks.

Scientific research provides some support for Eleutherococcus as a general adaptogen, with studies indicating potential benefits in improving physical endurance, cognitive function under stress, and mild anti-fatigue effects. However, direct evidence of eleutherosides specifically supporting adrenal gland function is limited and inconsistent. Most clinical studies have not directly measured adrenal hormones (like cortisol) or adrenal gland health, but rather overall stress response and fatigue. While animal and in vitro studies suggest possible modulation of the hypothalamic-pituitary-adrenal (HPA) axis, robust, well-controlled human trials validating significant effects on adrenal function are lacking.

In summary, the widespread use of Eleutheroside-containing Siberian ginseng to support the adrenal system is primarily based on traditional uses and indirect evidence regarding stress adaptation. The scientific evidence is suggestive but not definitive, meriting an evidence rating of 3 out of 5.

More about Eleutheroside
More about Adrenal Glands

Products containing Eleutheroside

We currently have no products on Vitabase that contain this ingredient.