Jatamansi (Nardostachys jatamansi) is traditionally used in Ayurvedic and other traditional medicine systems as an adaptogen and nervine tonic believed to support the adrenal glands and help the body cope with stress. The rationale behind its use for adrenal support comes from its reputation for calming the mind, reducing anxiety, and supporting restful sleep, all of which are considered beneficial for adrenal health in holistic frameworks. Historical Ayurvedic texts describe Jatamansi as having "medhya" (mind-enhancing) and "rasayana" (rejuvenating) properties, which are interpreted as helpful for the stress response and overall vitality—including adrenal function.

However, direct scientific evidence connecting Jatamansi specifically to adrenal gland health is limited. Some animal studies and preliminary research indicate that Jatamansi has anxiolytic, neuroprotective, and stress-reducing effects, which could theoretically reduce the burden on the adrenal glands by modulating the hypothalamic-pituitary-adrenal (HPA) axis. But these effects have not been robustly demonstrated in human clinical trials, and there is no direct evidence that Jatamansi improves adrenal gland function specifically.

In summary, the use of Jatamansi for adrenal support is primarily justified by traditional use and indirect evidence related to stress reduction, rather than by rigorous scientific validation targeting the adrenal glands themselves.