Evidence supporting the use of: Mexican Sarsaparilla
For the body system: Adrenal Glands

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Mexican Sarsaparilla (Smilax spp.) has a long history of traditional use in herbal medicine, including in Mexico and Central America. It has been used for a variety of indications, such as supporting hormonal balance, addressing skin conditions, and as a general tonic. Traditional herbalists sometimes associate sarsaparilla with supporting the adrenal glands, likely due to its reputed role in promoting stamina and resilience, although this association is more anecdotal than well-documented in classic ethnobotanical literature.

From a scientific standpoint, Mexican Sarsaparilla contains compounds such as saponins and phytosterols, which have been studied for their anti-inflammatory and immunomodulatory effects. However, there is little to no direct clinical or experimental evidence linking sarsaparilla to specific adrenal support or to influencing adrenal hormone production (such as cortisol or aldosterone). Most references to its use for adrenal health are found in popular herbal lore or alternative medicine literature, rather than in peer-reviewed scientific studies.

In summary, while there is a traditional basis for using Mexican Sarsaparilla as a general tonic and for vitality—attributes sometimes associated with adrenal health—the evidence for its direct support of the adrenal glands is weak and not well supported by rigorous scientific research.

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