Evidence supporting the use of: Porcine (unspecified)
For the body system: Adrenal Glands

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Porcine (unspecified), often referring to extracts derived from pig organs, has a long-standing history of use in traditional medicine and early 20th-century naturopathic practices to support adrenal gland function. The rationale stems from the concept of "like supports like," where consuming animal glandular tissue was believed to bolster the corresponding human organ. This approach was especially popular before the development of synthetic corticosteroids and other hormone replacement therapies. While animal adrenal extracts were once prescribed for conditions such as Addison’s disease and general fatigue, their use has largely diminished due to concerns about safety, inconsistent potency, and the advent of more effective pharmaceutical alternatives.

Modern scientific validation for porcine adrenal extracts is minimal. There are no robust clinical trials demonstrating their efficacy in supporting human adrenal function or treating adrenal insufficiency. Regulatory agencies such as the FDA have not approved glandular extracts for adrenal health, and most evidence remains anecdotal or stems from historical accounts. As a result, while porcine extracts are still found in some dietary supplements marketed for adrenal support, their use is primarily justified by tradition rather than scientific evidence.

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