Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Reishi (Ganoderma lucidum), also called "Lingzhi" in traditional Chinese medicine (TCM), has a long history of use for supporting vitality, stress adaptation, and general wellness. In TCM and other traditional systems, Reishi is classified as an adaptogen—an herb believed to help the body resist various stressors, which are thought to impact the adrenal glands. Traditional texts attribute to Reishi the ability to "calm the spirit" and "nourish Qi," qualities interpreted by modern practitioners as related to adrenal function and stress resilience.

However, scientific studies on Reishi's direct effects on adrenal glands or adrenal hormones (like cortisol) in humans are limited and inconclusive. Most research focuses on its immune-modulating, anti-inflammatory, and antioxidant properties, rather than specific support of adrenal health. Some animal studies suggest Reishi extracts may influence stress responses, but the mechanisms—such as modulation of the hypothalamic-pituitary-adrenal (HPA) axis—are not well established in humans.

In summary, the use of Reishi to support adrenal glands is primarily based on traditional principles, and while it is widely used for this purpose in herbal practice, modern scientific validation for direct adrenal support remains weak. The evidence rating reflects the strong traditional use but only modest support from scientific research.

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