Evidence supporting the use of: Rhodiola crenulata
For the body system: Adrenal Glands

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Rhodiola crenulata has a long history of traditional use in supporting the body's response to stress, which is often associated with the function of the adrenal glands. In traditional Chinese and Tibetan medicine, Rhodiola species, including R. crenulata, have been used as adaptogens—herbs thought to help the body resist physical, chemical, and biological stressors. The rationale for its use in supporting the "adrenal glands" is rooted in the adaptogenic concept, where these herbs are believed to balance and restore normal physiological functions, including stress hormone (cortisol) modulation. Although there are some modern clinical studies on Rhodiola rosea, a closely related species, showing benefits in reducing fatigue and improving stress tolerance, direct scientific evidence specifically linking R. crenulata to measurable improvements in adrenal gland function or adrenal hormone regulation is limited. Most of the support for this use comes from traditional practices and the broader adaptogenic effects observed in animal and preliminary human studies. Therefore, while there is traditional justification and some indirect scientific rationale, robust clinical trials directly validating the effect of Rhodiola crenulata on adrenal health are lacking.

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