Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Sarsaparilla (Smilax spp.) has a long history of use in traditional herbal medicine, particularly in Central and South America, and was popularized in 19th-century Western herbalism. Historically, sarsaparilla has been used as a general tonic, a blood purifier, and for treating skin conditions, but its specific use to "support the adrenal glands" is primarily rooted in modern herbal traditions rather than in scientific literature. In modern alternative medicine, sarsaparilla is sometimes included in formulas marketed for adrenal support, usually based on the idea that its general tonic and anti-inflammatory properties may help the body cope with stress. However, there is no robust scientific evidence directly linking sarsaparilla to improved adrenal gland function, cortisol regulation, or treatment of adrenal fatigue. Most research on sarsaparilla focuses on its saponins, antioxidant, and possible anti-inflammatory effects, but these do not specifically address adrenal health. Therefore, while its use for adrenal support is common in herbalist circles and tradition, it is not substantiated by clinical trials or pharmacological studies targeting adrenal gland function.

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