Synopsis

Source of validity: Traditional
Rating (out of 5): 2

White Peony (Paeonia lactiflora) has a long history of use in Traditional Chinese Medicine (TCM), where it is often prescribed as part of herbal formulas to support overall vitality, balance the body's energy (Qi), and address symptoms such as fatigue and stress—conditions now sometimes associated with "adrenal fatigue" in popular alternative health circles. In TCM, White Peony is believed to "nourish the blood" and "calm the liver," which practitioners sometimes connect to supporting the body's resilience to stress.

However, the concept of "adrenal support" as understood in Western medicine is not directly equivalent to TCM diagnostic categories. While there are animal and laboratory studies that suggest Paeonia lactiflora may have anti-inflammatory and immunomodulatory effects, and some evidence that its main active component, paeoniflorin, can influence stress-related biological pathways, there are no robust human clinical trials specifically linking White Peony to measurable improvements in adrenal gland function or hormone levels.

Therefore, the use of White Peony for adrenal support is justified primarily by traditional use rather than scientific validation. The evidence for its specific effects on the adrenal glands is weak and indirect, earning it an evidence rating of 2 out of 5.

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