Evidence supporting the use of: Eleutherococcus senticosus
For the body system: Adrenal Medulla

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Eleutherococcus senticosus, commonly known as Siberian ginseng, is traditionally used in herbal medicine as an adaptogen—a substance thought to help the body resist stressors of all kinds. Its use to support the adrenal medulla specifically stems from its adaptogenic reputation, as the adrenal medulla plays a key role in the stress response by secreting catecholamines like adrenaline and noradrenaline. Historical records, especially from Russian and Chinese herbal traditions, suggest that Eleutherococcus was employed to improve stamina, enhance resilience to stress, and boost energy levels. While there is a significant body of traditional use, direct scientific evidence linking Eleutherococcus senticosus to specific support of the adrenal medulla is limited. Some modern studies do indicate modest effects of Eleutherococcus on general stress adaptation and fatigue reduction, but these do not isolate effects on the adrenal medulla itself. Most research focuses on immune modulation and cognitive effects. Thus, while its use in supporting the adrenal medulla is rooted in tradition and the broader adaptogen concept, the scientific evidence for adrenal medulla-specific action is weak. The overall evidence rating for this use is therefore a 2, reflecting a predominance of traditional use and limited scientific validation for this specific application.

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