Evidence supporting the use of: Holy Basil Herb
For the body system: Adrenal Medulla

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Holy Basil (Ocimum sanctum, also known as Tulsi) has a long history of use in traditional Ayurvedic medicine as an adaptogen, a substance believed to help the body resist stressors of all kinds. In traditional practice, Holy Basil is said to support the body’s response to stress, which is linked to adrenal function, including the adrenal medulla—the part of the adrenal gland involved in producing catecholamines like adrenaline and noradrenaline. There is, however, limited direct scientific investigation specifically on Holy Basil’s effects on the adrenal medulla itself. Most available research focuses on its general stress-relieving, anti-anxiety, and anti-inflammatory properties, which are thought to indirectly support adrenal health by modulating the body’s stress response. Some animal studies and small human trials suggest that Holy Basil may reduce physiological markers of stress, but these do not directly measure adrenal medulla function. Therefore, while the use of Holy Basil for adrenal support is primarily rooted in tradition, with some supportive but indirect scientific evidence, there is insufficient direct scientific validation for its effects specifically on the adrenal medulla.

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