Evidence supporting the use of: Rhodiola (unspecified)
For the body system: Adrenal Medulla

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rhodiola (Rhodiola rosea) has a long history of use in traditional medicine systems, particularly in Russia, Scandinavia, and other parts of Eurasia. It is classified as an adaptogen—a substance believed to help the body resist physical, chemical, and biological stressors. Traditional use has focused on enhancing resilience to stress and fatigue, and helping with mood and cognitive function. While the adrenal glands are often mentioned in discussions about adaptogens, most references are to supporting the adrenal cortex (which produces cortisol and other steroid hormones) rather than the adrenal medulla (which produces catecholamines like adrenaline and noradrenaline).

There is limited direct scientific evidence connecting Rhodiola specifically to support of the adrenal medulla as a discrete body system. Most studies focus on Rhodiola’s general anti-fatigue, anti-stress, and cognitive effects, and reference its influence on the hypothalamic-pituitary-adrenal (HPA) axis rather than the adrenal medulla per se. Some research indicates potential modulation of catecholamine levels (which are produced in the adrenal medulla), but these findings are not robust or specific enough to establish a direct link. Therefore, the use of Rhodiola to support the adrenal medulla is primarily based on traditional beliefs about adaptogens, with only limited and indirect scientific exploration.

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