Evidence supporting the use of: Diclofenac
For the health condition: Afterbirth Pain

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that is scientifically validated for use in the management of afterbirth pain, also known as postpartum uterine pain. Afterbirth pain results from uterine contractions as the uterus returns to its pre-pregnancy size, especially noticeable in women who have had previous pregnancies. The pain is mediated by prostaglandins, which sensitize uterine muscle and pain pathways.

Diclofenac works by inhibiting the cyclooxygenase (COX) enzymes, thereby reducing prostaglandin synthesis. This mechanism directly addresses the underlying cause of afterbirth pain. Multiple clinical studies and reviews have demonstrated the effectiveness of NSAIDs, including diclofenac, in reducing moderate to severe postpartum pain, both after vaginal and cesarean deliveries. Diclofenac may be administered orally or as a rectal suppository, and has been shown to provide significant relief compared to placebo and is at least as effective as other NSAIDs like ibuprofen. Systematic reviews, such as Cochrane reviews on postpartum pain management, recognize NSAIDs as a mainstay of therapy for afterbirth pain. However, diclofenac’s evidence rating is not the highest possible (5/5) because most studies group it with other NSAIDs and direct head-to-head comparisons are limited.

In summary, the use of diclofenac for afterbirth pain is grounded in its well-understood pharmacology and supported by clinical evidence, making it a scientifically supported treatment option in appropriate postpartum patients.

More about Diclofenac
More about Afterbirth Pain

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