Evidence supporting the use of: Ferulic acid
For the health condition: Age Spots
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Ferulic acid is a plant-derived antioxidant commonly included in skincare products targeting hyperpigmentation and age spots (solar lentigines). Its scientific basis rests on its potent ability to neutralize free radicals and inhibit oxidative stress, both of which are implicated in the formation and darkening of age spots due to cumulative sun exposure and aging. In vitro studies have demonstrated that ferulic acid can suppress melanogenesis by inhibiting the activity of tyrosinase, a key enzyme involved in melanin production. Additionally, ferulic acid boosts the photoprotective effects of other antioxidants like vitamins C and E, helping to prevent further pigment accumulation when used in topical serums. Clinical evidence supporting ferulic acid for age spots is modest but growing. Some small-scale human studies and case series report improvements in hyperpigmentation and skin tone when ferulic acid is a component of combination antioxidant formulations. However, there is a lack of large, high-quality randomized controlled trials specifically examining ferulic acid as a solo treatment for age spots. The bulk of available data comes from its use in multi-ingredient products, making it difficult to isolate its individual effect. In summary, while there is a plausible scientific mechanism and preliminary evidence for ferulic acid in addressing age spots, the overall clinical evidence remains limited, warranting a moderate evidence rating.
Other ingredients used for Age Spots
aloe verachamomile
turmeric
green tea
lavender
licorice root
niacinamide (vitamin B3)
polypeptide complex (proprietary)
vitamin A
vitamin C
vitamin E
ferulic acid
polyphenols
Apple Cider Vinegar
Azelaic acid
Arbutin
Alpha Hydroxy Acids
Calendula
Epidermal Growth Factor
Ellagic Acid
Flavonoids
Other health conditions supported by ferulic acid
Age SpotsAlzheimer's Disease
Arthritis
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cholesterol (high)
Diabetes
Diabetic Retinopathy
Fatty Liver Disease
Free Radical Damage
Hypertension
Inflammation
Memory and Brain Function
Parkinson's Disease
Psoriasis
Wrinkles