Evidence supporting the use of: β-nicotinamide mononucleotide (NMN)
For the health condition: Aging (prevention)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

β-nicotinamide mononucleotide (NMN) is a molecule naturally found in the body and is a direct precursor to nicotinamide adenine dinucleotide (NAD+), a crucial coenzyme involved in cellular energy metabolism and DNA repair. Interest in NMN as a supplement for aging prevention arises from research demonstrating that NAD+ levels decline with age, which may contribute to the aging process and age-related diseases. Animal studies, especially in mice, have shown that NMN supplementation can increase NAD+ levels, improve various markers of metabolic and vascular health, enhance physical activity, and even extend lifespan in some cases. These findings have made NMN a subject of significant scientific interest as a potential anti-aging intervention.

However, human data are still limited. Early clinical trials indicate that NMN supplementation is safe and well-tolerated, and may modestly improve some aspects of metabolism and cardiovascular function. No large-scale, long-term studies have yet proven that NMN supplementation delays aging or extends human lifespan. Therefore, while the use of NMN is based on a plausible scientific rationale and promising preclinical results, the strength of evidence in humans remains preliminary, justifying a moderate-low score (2/5). NMN is not a traditional remedy and its use is supported primarily by recent scientific investigation rather than historical practice.

More about β-nicotinamide mononucleotide (NMN)
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Other ingredients used for Aging (prevention)

7-hydroxymatairesinol (HMR)
7-Keto-DHEA
Acai berry
Acetyl L-carnitine
Akkermansia muciniphila
algal oil
Alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
Brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
L-carnosine
lutein
magnesium
Matcha
Melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
Rhodiola
selenium
silicon
soybean
Trans-pterostilbene
Almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
Watermelon
Zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
Yerba mate
goji berry
Algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
antler
apigenin
Aronia melanocarpa
Antrodia camphorata
anserine
avocado
Alpha hydroxy acids
Allantoin
alpha-lipoic acid
astragaloside
anthocyanidins
ampelopsin
Algal protein
anthocyanosides
argan nut oil
Abalone
Brassica
bioflavonoids
bird\'s nest
Carnosine
Curcuminoid
cruciferous
cycloastragenol
Chinese Ligustrum berry
carotene (unspecified)
Dunaliella salina
dismutase
DHEA
Dunaliella
Epidermal Growth Factor
epicatechin
ellagic acid
ergothioneine
flavonoids
fo-ti
fucoxanthin
fibroblast growth factor
Ginsenosides
Gac
Gerovital H3
Glabridin
hydroxymethylbutyrate
Haematococcus pluvialis
HMB hydroxymethylbutyrate
hazelnut
icariin
Lycium
Oligomeric proanthocyanidins
oolong tea
pyrroloquinoline quinone
Phytofluene
Phytoene
Peptides
Squalene
Salidroside
Shilajit
Triterpenes
Tremella
Xanthophyll

Products containing β-nicotinamide mononucleotide (NMN)

Designs For Health Liposomal NMN Synergy 1.7 fl oz (50 ml) liquid. Nonreturnable item.