Evidence supporting the use of: Aloe Polysaccharide
For the health condition: Aging (prevention)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Aloe polysaccharides, particularly acemannan, have been studied for their potential anti-aging properties. Scientific research suggests that these polysaccharides possess antioxidant, anti-inflammatory, and immunomodulatory effects, all of which are relevant to the biology of aging. In vitro and animal studies indicate that aloe polysaccharides can scavenge free radicals, reduce oxidative stress, and support skin health by promoting collagen synthesis and wound healing. Some small clinical trials have reported that oral or topical aloe extracts may improve skin elasticity and reduce the appearance of wrinkles, likely due to enhanced hydration and stimulation of fibroblasts.
However, the clinical evidence in humans specifically addressing aging prevention is limited in both scale and rigor. Most studies involve whole aloe vera gel or extracts rather than purified polysaccharides, and sample sizes are often small. While there is a plausible biological basis and some supportive preclinical data, robust, large-scale human trials are lacking. Thus, while aloe polysaccharides are sometimes marketed for anti-aging benefits and there is early scientific interest, the overall quality and quantity of evidence supporting their use for aging prevention is moderate at best.
More about Aloe Polysaccharide
More about Aging (prevention)
Other ingredients used for Aging (prevention)
7-hydroxymatairesinol (HMR)7-Keto-DHEA
acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
l-carnosine
lutein
magnesium
matcha
melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
rhodiola
sardines
selenium
silicon
soybean
trans-pterostilbene
almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
watermelon
zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
yerba mate
goji berry
algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
Antler
Apigenin
Aronia melanocarpa
Antrodia camphorata
Anserine
Avocado
Alpha Hydroxy Acids
Allantoin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Algal protein
anthocyanosides
Argan nut oil
Abalone
Brassica
Bioflavonoids
Bird's nest
Carnosine
Curcuminoid
Cruciferous
Cycloastragenol
Chinese Ligustrum berry
Carotene (unspecified)
Dunaliella salina
Dismutase
DHEA
Dunaliella
Epidermal Growth Factor
epicatechin
Ellagic Acid
Ergothioneine
Flavonoids
fibroblast growth factor
Other health conditions supported by Aloe Polysaccharide
Abdominal PainAbrasions
Acid Indigestion
Aging (prevention)
Arthritis
Bites and Stings
Bladder Infection
Bleeding (external)
Burns and Scalds
Cancer Treatment (reducing side effects)
Canker Sores
Colitis
Constipation (adults)
Cuts
Dermatitis
Diabetes
Diaper Rash
Diarrhea
Digestion (poor)
Eczema
Gastritis
Gingivitis
Hepatitis
Herpes
Indigestion
Infection
Inflammation
Inflammatory Bowel Disorders
Injuries
Irritable Bowel Syndrome
Itching
Lesions
Oral Surgery
Psoriasis
Rashes and Hives
Scars / Scar Tissue
Scratches and Abrasions
Skin (dry and/or flaky)
Skin (infections)
Skin Care (general)
Sunburn
Ulcers
Wounds and Sores