Evidence supporting the use of: Apple
For the health condition: Aging (prevention)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Apples have been studied for their potential anti-aging benefits, primarily due to their high content of polyphenols, flavonoids, and dietary fiber. Scientific research has identified that apples are rich in antioxidants such as quercetin, catechin, and chlorogenic acid, which help neutralize free radicals—a key mechanism implicated in cellular aging and age-related diseases. Epidemiological studies have associated regular apple consumption with reduced risk of chronic diseases like cardiovascular disease, type 2 diabetes, and certain cancers, all of which are linked to the aging process. Animal and in vitro studies suggest that apple extracts can improve lifespan and healthspan by reducing oxidative stress and inflammation. However, while these findings are promising, high-quality clinical trials specifically investigating apples' direct effects on aging or longevity in humans remain limited. Most evidence is extrapolated from general improvements in health markers rather than direct anti-aging effects. Thus, while there is a reasonable scientific basis to support the role of apples in maintaining health and potentially slowing some aging processes, the evidence is currently moderate and not definitive. Further research, particularly long-term human studies, is needed for a stronger validation of apple’s role in aging prevention.

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Other ingredients used for Aging (prevention)

7-hydroxymatairesinol (HMR)
7-Keto-DHEA
acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
l-carnosine
lutein
magnesium
matcha
melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
rhodiola
sardines
selenium
silicon
soybean
trans-pterostilbene
almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
watermelon
zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
yerba mate
goji berry
algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
Antler
Apigenin
Aronia melanocarpa
Antrodia camphorata
Anserine
Avocado
Alpha Hydroxy Acids
Allantoin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Algal protein
anthocyanosides
Argan nut oil
Abalone
Brassica
Bioflavonoids
Bird's nest
Carnosine
Curcuminoid
Cruciferous
Cycloastragenol
Chinese Ligustrum berry
Carotene (unspecified)
Dunaliella salina
Dismutase
DHEA
Dunaliella
Epidermal Growth Factor
epicatechin
Ellagic Acid
Ergothioneine
Flavonoids
fibroblast growth factor