Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ashitaba (Angelica keiskei) is traditionally consumed in Japan and has gained attention for its potential anti-aging properties. Scientific studies in recent years have investigated its bioactive compounds, especially chalcones such as 4-hydroxyderricin and xanthoangelol. These compounds have demonstrated antioxidant, anti-inflammatory, and autophagy-inducing effects in cell and animal models. In particular, a 2019 study published in Nature Communications found that ashitaba chalcones could extend the lifespan of fruit flies and increase healthspan in mice by enhancing autophagy, a cellular process associated with aging and age-related diseases.

Other research suggests that ashitaba may help combat oxidative stress, a primary contributor to cellular aging, by scavenging free radicals and upregulating endogenous antioxidant enzymes. However, while these preclinical results are promising, there is currently a lack of robust clinical trials in humans directly linking ashitaba consumption to measurable anti-aging benefits. Thus, while the evidence is more scientific than purely traditional, it remains preliminary, and further research is needed to confirm its anti-aging effects in humans. Overall, ashitaba’s use as an anti-aging supplement is supported by promising but early scientific evidence rather than long-standing traditional use for this purpose.

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