Evidence supporting the use of: Epicatechin
For the health condition: Aging (prevention)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Epicatechin, a flavonoid abundant in cocoa, green tea, and some fruits, has been investigated for its potential anti-aging effects, particularly due to its antioxidant properties and impact on cellular health. Preclinical studies in animals and cell models have shown that epicatechin can improve mitochondrial function, enhance muscle growth, and reduce oxidative stress—all factors implicated in aging. Some research suggests that epicatechin can upregulate the expression of genes involved in longevity and cellular repair, and may improve vascular function, which typically declines with age.
However, human evidence is limited. Small-scale trials have indicated improvements in endothelial function and insulin sensitivity, which could conceivably play a role in healthy aging. Despite these promising findings, there are currently no large, long-term clinical trials demonstrating that epicatechin supplementation slows the aging process or prevents age-related diseases in humans. Most of the support for its use in aging prevention comes from animal studies and mechanistic research rather than direct clinical outcomes. Thus, while there is scientific interest and some preliminary evidence, the current level of support is modest and further research is needed to establish clear benefits in humans.
Other ingredients used for Aging (prevention)
7-hydroxymatairesinol (HMR)7-Keto-DHEA
acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
l-carnosine
lutein
magnesium
matcha
melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
rhodiola
sardines
selenium
silicon
soybean
trans-pterostilbene
almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
watermelon
zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
yerba mate
goji berry
algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
Antler
Apigenin
Aronia melanocarpa
Antrodia camphorata
Anserine
Avocado
Alpha Hydroxy Acids
Allantoin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Algal protein
anthocyanosides
Argan nut oil
Abalone
Brassica
Bioflavonoids
Bird's nest
Carnosine
Curcuminoid
Cruciferous
Cycloastragenol
Chinese Ligustrum berry
Carotene (unspecified)
Dunaliella salina
Dismutase
DHEA
Dunaliella
Epidermal Growth Factor
epicatechin
Ellagic Acid
Ergothioneine
Flavonoids
fibroblast growth factor
Other health conditions supported by epicatechin
Aging (prevention)Alzheimer's Disease
Arteriosclerosis
Cancer (natural therapy for)
Cancer (prevention)
Cardiovascular Disease
Circulation (poor)
Diabetes
Fatty Liver Disease
Free Radical Damage
Hypertension
Inflammation
Memory and Brain Function
Osteoporosis
Ulcers
Wounds and Sores