Evidence supporting the use of: Oligomeric proanthocyanidins
For the health condition: Aging (prevention)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Oligomeric proanthocyanidins (OPCs) are polyphenolic compounds primarily found in grape seeds, pine bark, and certain other plants. Their use in supporting aging or preventing age-related decline is primarily based on their antioxidant properties. Scientific studies have documented that OPCs are potent free radical scavengers, which may help protect cells from oxidative stress—a process implicated in cellular aging and the progression of age-related diseases. Some in vitro and animal studies suggest that OPCs may benefit vascular health, skin elasticity, and cognitive function by reducing oxidative damage and inflammation.

However, the direct evidence supporting the use of OPCs specifically for aging prevention in humans is limited. While some small clinical trials suggest benefits for skin health (such as improved elasticity and reduced wrinkles) and cardiovascular markers, the overall body of evidence is not robust, with most studies being short-term, involving small sample sizes, or focusing on surrogate outcomes rather than direct measures of aging or longevity. No large-scale, long-term clinical trials have definitively shown that OPC supplementation slows or prevents the aging process in humans.

In summary, while there is a scientific rationale and some preliminary clinical evidence for the use of OPCs in mitigating mechanisms related to aging, the quality and quantity of human data are modest. Thus, the use of OPCs for aging prevention is best described as having limited scientific support at this time.

More about Oligomeric proanthocyanidins
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Other ingredients used for Aging (prevention)

7-hydroxymatairesinol (HMR)
7-Keto-DHEA
acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
l-carnosine
lutein
magnesium
matcha
melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
rhodiola
sardines
selenium
silicon
soybean
trans-pterostilbene
almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
watermelon
zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
yerba mate
goji berry
algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
Antler
Apigenin
Aronia melanocarpa
Antrodia camphorata
Anserine
Avocado
Alpha Hydroxy Acids
Allantoin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Algal protein
anthocyanosides
Argan nut oil
Abalone
Brassica
Bioflavonoids
Bird's nest
Carnosine
Curcuminoid
Cruciferous
Cycloastragenol
Chinese Ligustrum berry
Carotene (unspecified)
Dunaliella salina
Dismutase
DHEA
Dunaliella
Epidermal Growth Factor
epicatechin
Ellagic Acid
Ergothioneine
Flavonoids
fibroblast growth factor

Products containing Oligomeric proanthocyanidins

We currently have no products on Vitabase that contain this ingredient.