Evidence supporting the use of: Peptide
For the health condition: Aging (prevention)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Peptides are short chains of amino acids that serve as the building blocks of proteins. In the context of aging prevention, peptides—particularly those used in topical skincare—have garnered significant scientific interest. Several clinical and laboratory studies suggest that certain peptides (such as palmitoyl pentapeptide-4, copper peptides, and others) can stimulate collagen production, enhance skin barrier function, and reduce the appearance of fine lines and wrinkles. These effects are primarily based on the peptides’ ability to signal skin cells to perform specific functions, such as repairing damage or synthesizing extracellular matrix components.

Reviews and meta-analyses of randomized controlled trials indicate modest but measurable improvements in skin elasticity, hydration, and wrinkle depth with consistent use of peptide-containing products. For example, a 2019 review in the journal Dermatologic Therapy highlighted that topical peptides can enhance skin firmness and decrease wrinkle volume over several weeks of use. However, while the evidence supports peptides’ role in cosmetic improvement and skin aging prevention, the overall clinical effect is moderate and may vary depending on formulation and individual response.

It is important to note that most evidence pertains to topical application for skin aging, with less support for systemic (oral or injectable) peptide supplements in preventing general aging. Thus, peptides are scientifically validated—particularly in dermatology—for their role in skin aging prevention, though not as a broad anti-aging remedy.

More about Peptide
More about Aging (prevention)

Other ingredients used for Aging (prevention)

7-hydroxymatairesinol (HMR)
7-Keto-DHEA
acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
l-carnosine
lutein
magnesium
matcha
melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
rhodiola
sardines
selenium
silicon
soybean
trans-pterostilbene
almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
watermelon
zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
yerba mate
goji berry
algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
Antler
Apigenin
Aronia melanocarpa
Antrodia camphorata
Anserine
Avocado
Alpha Hydroxy Acids
Allantoin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Algal protein
anthocyanosides
Argan nut oil
Abalone
Brassica
Bioflavonoids
Bird's nest
Carnosine
Curcuminoid
Cruciferous
Cycloastragenol
Chinese Ligustrum berry
Carotene (unspecified)
Dunaliella salina
Dismutase
DHEA
Dunaliella
Epidermal Growth Factor
epicatechin
Ellagic Acid
Ergothioneine
Flavonoids
fibroblast growth factor

Products containing Peptide

We currently have no products on Vitabase that contain this ingredient.