Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Resveratrol is a polyphenolic compound found in foods like grapes, red wine, and berries. Its use in aging prevention is supported by scientific research, primarily from preclinical studies. In laboratory experiments, resveratrol has been shown to activate sirtuin proteins (especially SIRT1), which are associated with increased cellular lifespan and enhanced DNA repair mechanisms. Animal studies, particularly in mice and other lower organisms, have demonstrated that resveratrol can mimic some effects of caloric restriction—a well-known intervention to extend lifespan in various species. These findings have generated significant interest in resveratrol as a potential anti-aging compound.

However, human studies are limited and results are mixed. Some small clinical trials have indicated potential benefits of resveratrol supplementation on markers of metabolic health, inflammation, and vascular function in older adults, but there is no strong evidence that it significantly slows aging or extends human lifespan. The compound’s bioavailability in humans is also quite low, raising questions about its effectiveness at typical supplemental doses. As such, while there is a scientific rationale and promising animal data, the clinical evidence in humans is not strong enough to conclusively support resveratrol as an anti-aging intervention. More large-scale, long-term studies in humans are needed to determine its true efficacy in aging prevention.

More about resveratrol
More about Aging (prevention)

Other ingredients used for Aging (prevention)

Other health conditions supported by resveratrol

Products containing resveratrol

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