Evidence supporting the use of: Resveratrol analog (unspecified)
For the health condition: Aging (prevention)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Resveratrol analogs are synthetic or naturally occurring compounds structurally similar to resveratrol, a polyphenol found in red wine, grapes, and some berries. Scientific interest in these compounds centers on their potential to mimic or enhance the biological activities of natural resveratrol, particularly in the context of aging and age-related diseases. Preclinical studies (in vitro and animal models) have shown that resveratrol and some of its analogs can activate sirtuin pathways, notably SIRT1, which are linked to improved cellular health, enhanced stress resistance, and lifespan extension in lower organisms (such as yeast, worms, and flies). Additionally, resveratrol analogs may exhibit better bioavailability or potency compared to natural resveratrol, addressing a limitation of the parent compound. However, despite promising laboratory data, robust evidence from human clinical trials remains lacking. To date, there are no large-scale, long-term clinical studies specifically demonstrating that resveratrol analogs prevent aging or extend human lifespan. Most human data are limited, inconclusive, or extrapolated from studies on resveratrol itself. Therefore, while there is a scientific rationale and some preliminary evidence supporting the investigation of resveratrol analogs for aging prevention, their use is not yet validated by strong clinical evidence. The overall evidence supporting their use for this purpose rates as low to moderate (2/5), pending further human research.
More about Resveratrol analog (unspecified)
More about Aging (prevention)
Other ingredients used for Aging (prevention)
7-hydroxymatairesinol (HMR)7-Keto-DHEA
acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
l-carnosine
lutein
magnesium
matcha
melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
rhodiola
sardines
selenium
silicon
soybean
trans-pterostilbene
almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
watermelon
zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
yerba mate
goji berry
algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
Antler
Apigenin
Aronia melanocarpa
Antrodia camphorata
Anserine
Avocado
Alpha Hydroxy Acids
Allantoin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Algal protein
anthocyanosides
Argan nut oil
Abalone
Brassica
Bioflavonoids
Bird's nest
Carnosine
Curcuminoid
Cruciferous
Cycloastragenol
Chinese Ligustrum berry
Carotene (unspecified)
Dunaliella salina
Dismutase
DHEA
Dunaliella
Epidermal Growth Factor
epicatechin
Ellagic Acid
Ergothioneine
Flavonoids
fibroblast growth factor
Other health conditions supported by Resveratrol analog (unspecified)
Aging (prevention)Alzheimer's Disease
Arthritis
Cancer (natural therapy for)
Cancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Diabetes
Diabetic Retinopathy
Fatty Liver Disease
Hypertension
Inflammation
Memory and Brain Function
Metabolic Syndrome
Osteoporosis
Parkinson's Disease
Rheumatoid Arthritis
Triglycerides (high)
Wrinkles