Relationship: Aging (prevention) and selenium

Evidence supporting the use of: Selenium
For the health condition: Aging (prevention)

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Source of validity: Scientific
Rating (out of 5): 2

Selenium is a trace mineral with antioxidant properties, and its role in aging and age-related diseases has been the subject of scientific investigation. Selenium is a cofactor for the enzyme glutathione peroxidase, which helps protect cells from oxidative damage by neutralizing free radicals. Since oxidative stress is a known contributor to the aging process and the development of age-related conditions, selenium has been hypothesized to have anti-aging benefits. Some population studies have observed that individuals with higher selenium status tend to have better cognitive function and may experience lower rates of age-related diseases, such as cardiovascular disease and certain cancers.

However, the evidence supporting selenium supplementation specifically for the prevention of aging in healthy adults is limited and mixed. Large randomized controlled trials, such as the SELECT trial, have not shown clear benefits of selenium supplementation in reducing the risk of major age-related diseases in well-nourished populations. There is also evidence that both selenium deficiency and excess can be harmful, and the margin between optimal and excessive intake is narrow. While selenium is essential for health and its deficiency can accelerate aging-related decline, supplementation beyond dietary needs does not have robust evidence for preventing aging itself. Thus, while there is a scientific rationale and some supporting data, the overall quality of evidence is low to moderate.

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Other ingredients used for Aging (prevention)

3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
7-hydroxymatairesinol (HMR)
7-Keto-DHEA
8-Prenylnaringenin
Abalone
Acai berry
Acetyl L-carnitine
Akkermansia muciniphila
Algae
algal oil
Algal protein
Allantoin
Almond fruit
Alpha hydroxy acids
Alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
alpha-lipoic acid
amino acids
AMP-activated protein kinase (AMPK)
ampelopsin
anemarrhena asphodeloides
anserine
anthocyanidins
anthocyanins
anthocyanosides
antler
Antrodia camphorata
apigenin
apple
apricot
argan nut oil
Aronia melanocarpa
ascorbyl palmitate
ashitaba
ashwagandha
astaxanthin
astragaloside
astragalus
avocado
beta-carotene
bioflavonoids
bird\'s nest
Brassica
Brussel sprouts
Carnosine
carotene (unspecified)
carrot
catalase
cauliflower
Chinese Ligustrum berry
cistanche
coenzyme Q10 (CoQ10)
collagen
cruciferous
cryptoxanthin
curcumin
Curcuminoid
cycloastragenol
DHEA
DHEA (dehydroepiandrosterone)
dismutase
dodder
Dunaliella
Dunaliella salina
ellagic acid
epicatechin
Epidermal Growth Factor
epigallocatechin gallate (EGCG)
ergothioneine
fibroblast growth factor
fisetin
flavonoids
flaxseed
fo-ti
fucoxanthin
Gac
Gerovital H3
ginkgo biloba
Ginsenosides
Glabridin
goji berry
green tea
greens blend (proprietary)
Haematococcus pluvialis
hazelnut
HMB hydroxymethylbutyrate
hydroxymethylbutyrate
icariin
L-carnosine
lutein
Lycium
magnesium
Matcha
Melatonin
mixed carotenoids
nicotinamide riboside
Oligomeric proanthocyanidins
omega-3 fatty acids
oolong tea
Peptides
Phytoene
Phytofluene
polypeptide complex (proprietary)
polyphenols
protein
pyrroloquinoline quinone
quercetin
resveratrol
Rhodiola
royal jelly
Salidroside
selenium
Shilajit
silicon
soy isoflavones
soybean
Squalene
Trans-pterostilbene
Tremella
Triterpenes
turmeric
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
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Yerba mate
Zinc
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Evidence supporting the use of: Selenium
For the health condition: Aging (prevention)

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Synopsis

Other ingredients used for Aging (prevention)

Other health conditions supported by selenium

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Health Concerns

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Evidence supporting the use of: SeleniumFor the health condition: Aging (prevention)

Table of Contents

Synopsis

Other ingredients used for Aging (prevention)

Other health conditions supported by selenium

Products containing selenium

Evidence supporting the use of: Selenium
For the health condition: Aging (prevention)