Evidence supporting the use of: SOD (Superoxide Dismutase, antioxidant activity)
For the health condition: Aging (prevention)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Superoxide Dismutase (SOD) is an endogenous antioxidant enzyme that plays a key role in protecting cells from oxidative stress by catalyzing the dismutation of superoxide radicals into oxygen and hydrogen peroxide. The rationale for using SOD in aging prevention is based on the "free radical theory of aging," which posits that accumulated oxidative damage contributes to the aging process and age-related diseases. Scientific studies in cell cultures and animal models have shown that enhancing SOD activity can reduce oxidative damage and, in some cases, extend lifespan or decrease markers of aging. For example, transgenic mice overexpressing SOD have demonstrated delayed onset of age-related pathologies. However, evidence in humans is limited. Oral supplementation with SOD is challenging because the enzyme is degraded in the gastrointestinal tract, though some formulations (e.g., coated or plant-derived SOD) aim to address this. Clinical trials in humans are few and generally small, with mixed or modest results regarding improvements in oxidative stress markers or subjective well-being. As such, while the theoretical and preclinical basis is strong, robust clinical evidence for SOD supplementation in aging prevention is lacking. Therefore, the use of SOD for aging prevention is supported by scientific rationale and some preliminary data, but definitive human evidence is currently insufficient.

More about SOD (Superoxide Dismutase, antioxidant activity)
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Other ingredients used for Aging (prevention)

7-hydroxymatairesinol (HMR)
7-Keto-DHEA
acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
l-carnosine
lutein
magnesium
matcha
melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
rhodiola
sardines
selenium
silicon
soybean
trans-pterostilbene
almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
watermelon
zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
yerba mate
goji berry
algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
Antler
Apigenin
Aronia melanocarpa
Antrodia camphorata
Anserine
Avocado
Alpha Hydroxy Acids
Allantoin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Algal protein
anthocyanosides
Argan nut oil
Abalone
Brassica
Bioflavonoids
Bird's nest
Carnosine
Curcuminoid
Cruciferous
Cycloastragenol
Chinese Ligustrum berry
Carotene (unspecified)
Dunaliella salina
Dismutase
DHEA
Dunaliella
Epidermal Growth Factor
epicatechin
Ellagic Acid
Ergothioneine
Flavonoids
fibroblast growth factor

Products containing SOD (Superoxide Dismutase, antioxidant activity)

We currently have no products on Vitabase that contain this ingredient.