Evidence supporting the use of: Vitamin B1 (Prosultiamine)
For the health condition: Alcoholism

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin B1 (Prosultiamine) is a derivative of thiamine, an essential nutrient. Thiamine deficiency is common in individuals with chronic alcoholism due to poor dietary intake, impaired absorption, and altered metabolism. This deficiency can lead to severe neurological complications such as Wernicke’s encephalopathy and Korsakoff’s psychosis. There is strong scientific evidence supporting the use of thiamine supplementation—including various forms such as prosultiamine—both for the prevention and treatment of these complications in alcohol-dependent patients. Numerous clinical guidelines (such as those from the National Institute for Health and Care Excellence and the World Health Organization) recommend routine supplementation of thiamine in individuals with alcoholism, especially prior to or during carbohydrate refeeding, to prevent acute neurological deterioration. Although most clinical studies focus on thiamine hydrochloride, prosultiamine is sometimes used due to its higher bioavailability and improved central nervous system penetration. However, direct evidence comparing the efficacy of prosultiamine to other forms of thiamine in alcoholic patients is limited. Overall, the rationale for using thiamine (including prosultiamine) in alcoholism is well established and based on a strong scientific foundation, though most data pertain to thiamine in general rather than prosultiamine specifically.

More about Vitamin B1 (Prosultiamine)
More about Alcoholism

Other health conditions supported by Vitamin B1 (Prosultiamine)

Alcoholism
Peripheral Neuropathy

Products containing Vitamin B1 (Prosultiamine)

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