Evidence supporting the use of: Vitamin B3 (Niacinamide)
For the health condition: Alcoholism

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Vitamin B3 (niacinamide) has a historical association with the treatment of alcoholism, primarily rooted in the orthomolecular medicine movement popularized by Dr. Abram Hoffer in the mid-20th century. Hoffer and colleagues claimed that high doses of vitamin B3 could reduce alcohol cravings and support recovery, based largely on anecdotal reports and small, uncontrolled case series. This approach became part of some traditional addiction treatment protocols, particularly in alternative medicine circles and certain recovery communities. However, rigorous scientific validation for the effectiveness of vitamin B3 in treating alcoholism is lacking. Modern clinical research does not support the claim that niacinamide or other forms of vitamin B3 have a significant impact on alcohol dependence, craving, or relapse prevention. Most reputable guidelines do not recommend niacinamide as a treatment for alcoholism, except in cases where chronic alcohol use has caused a deficiency of B vitamins, including niacin, leading to pellagra or other related symptoms. In summary, while the use of niacinamide to support alcoholism has traditional roots, particularly from alternative medicine models, its efficacy is not supported by strong scientific evidence.

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