Evidence supporting the use of: Lactococcus rhamnosus
For the health condition: Allergies (food)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactococcus rhamnosus (often referenced as Lactobacillus rhamnosus in older literature) has been studied for its potential to support or treat food allergies, particularly in children. The scientific evidence primarily comes from clinical trials examining its effects on allergic conditions such as atopic dermatitis and cow’s milk allergy. Some randomized controlled trials have shown that certain strains, most notably L. rhamnosus GG, may help modulate the immune response and promote tolerance to allergens. For example, supplementation with L. rhamnosus GG in infants with cow’s milk allergy has been associated with increased rates of oral tolerance acquisition in some studies.

However, the evidence remains mixed and not universally positive. Meta-analyses and systematic reviews report modest benefits at best, and some studies show no significant effects compared to placebo. The observed effects may depend on the strain used, the timing of intervention, the duration of supplementation, and the specific allergic condition.

In summary, there is a scientific rationale and some clinical evidence supporting the use of Lactococcus rhamnosus for food allergies, but findings are inconsistent and generally indicate only a modest benefit. Further large, well-designed studies are needed to clarify its efficacy and optimal use. The current level of evidence supports a rating of 2 out of 5.

More about Lactococcus rhamnosus
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