Evidence supporting the use of: Bacillus coagulans
For the health condition: Allergies (respiratory)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bacillus coagulans is a probiotic bacterium that has been studied for a variety of health benefits, including immune modulation. There is some emerging scientific evidence suggesting a potential role of B. coagulans in alleviating symptoms of respiratory allergies, such as allergic rhinitis. The proposed mechanism involves the modulation of the host immune response, specifically by balancing Th1/Th2 immune pathways, reducing pro-inflammatory cytokines, and enhancing regulatory T-cell activity. Several small-scale clinical trials and animal studies have investigated the ability of B. coagulans to reduce allergy-related inflammation and symptoms.

For example, a randomized, double-blind, placebo-controlled trial published in Food Research International (2019) indicated that supplementation with B. coagulans in individuals with allergic conditions resulted in a decrease in nasal symptoms and certain inflammatory markers. Other studies have demonstrated the ability of B. coagulans to modulate immune responses in models of allergy. However, the number of high-quality, large-scale clinical trials is limited, and most available studies are preliminary or involve small cohorts.

Overall, while there is some scientific rationale and early clinical evidence supporting the use of B. coagulans for respiratory allergies, the strength of the evidence is still modest. More rigorous and larger studies are needed to confirm its efficacy and determine optimal dosing and patient populations. Therefore, the evidence rating is 2 out of 5.

More about bacillus coagulans
More about Allergies (respiratory)