Evidence supporting the use of: Bacteria
For the health condition: Allergies (respiratory)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

There is growing scientific evidence supporting the use of certain bacteria, specifically probiotic strains, to help manage and prevent respiratory allergies such as allergic rhinitis and asthma. The rationale is based on the role of the gut and airway microbiome in modulating immune responses. Several randomized controlled trials and meta-analyses have investigated the effects of probiotics—most commonly species of Lactobacillus and Bifidobacterium—on allergic conditions. Some studies have shown that probiotics can help reduce the severity of symptoms, decrease the frequency of episodes, and improve quality of life in individuals with respiratory allergies, particularly in children. The proposed mechanism involves modulation of the immune system, including promoting regulatory T cell responses and shifting the immune balance away from the allergy-promoting Th2 phenotype.

However, the results are not universally consistent. Some studies show little or no benefit, and there is variability depending on the probiotic strain, dosage, duration, and the specific allergic condition. Major scientific bodies acknowledge the potential but note that the evidence is not yet robust enough to recommend probiotics as a standard treatment for respiratory allergies. Further high-quality, large-scale studies are needed to clarify which strains are most effective and in which populations. Nevertheless, current evidence does provide a scientific basis for the use of certain bacteria to support the management of respiratory allergies, justifying a moderate evidence rating.

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