Evidence supporting the use of: Bupleurum (unspecified)
For the health condition: Allergies (respiratory)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Bupleurum is a traditional herb widely used in Chinese medicine, most notably as a component of the formula Xiao Chai Hu Tang and related preparations. Its primary historical use has been for the treatment of "Shaoyang syndrome," liver stagnation, and to harmonize the body's internal states. In traditional Chinese medicine (TCM), Bupleurum is sometimes used in formulas aimed at treating respiratory allergies, such as allergic rhinitis or hay fever, based on its reputed abilities to "soothe the liver," reduce inflammation, and modulate the immune response.

However, direct scientific evidence for Bupleurum's efficacy in treating respiratory allergies is limited. While some laboratory studies have identified anti-inflammatory and immunomodulatory effects of Bupleurum extracts and their constituent saikosaponins, there is a lack of well-designed clinical trials specifically addressing allergic conditions in humans. Most contemporary uses for allergies are extrapolated from its general use in inflammatory and immune-related conditions within traditional practice.

In summary, Bupleurum's use for respiratory allergies is primarily rooted in traditional medicine and expert consensus within TCM, with modest supportive evidence from basic pharmacological research. There is insufficient clinical evidence to strongly support its efficacy for this specific indication by Western scientific standards.

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