Evidence supporting the use of: Licorice root
For the health condition: Allergies (respiratory)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Licorice root (Glycyrrhiza glabra) has a long history of use in traditional medicine systems such as Traditional Chinese Medicine (TCM) and Ayurveda for alleviating respiratory ailments, including those related to allergies. In TCM, licorice is known as "Gan Cao" and is commonly included in herbal formulas to harmonize other ingredients and to soothe the respiratory tract. Traditionally, it has been used to relieve symptoms such as cough, sore throat, and inflammation associated with allergic reactions and respiratory conditions.

The rationale for its use in allergies is based on licorice’s reputed anti-inflammatory, demulcent (soothing), and immune-modulating properties. Licorice root contains glycyrrhizin, which is thought to have corticosteroid-like effects, potentially reducing inflammation in the airways. However, while in vitro and animal studies suggest some anti-inflammatory and immunomodulatory effects, there is limited direct clinical evidence specifically supporting its efficacy for treating respiratory allergies in humans. Most supporting data are extrapolated from its general anti-inflammatory activity and traditional use, rather than from high-quality human trials for allergic rhinitis or asthma.

Therefore, while licorice root is widely used in traditional medicine for respiratory support, including allergic conditions, the evidence base remains weak, and more rigorous clinical studies are needed to validate its efficacy and safety for this specific indication.

More about licorice root
More about Allergies (respiratory)

Other health conditions supported by licorice root

Abdominal Pain
Abrasions
Abscesses
Acid Indigestion
Acne
Addictions (general remedies for)
Addictions (tobacco smoking or chewing)
Addison's Disease
Adenitis
Adrenal Fatigue
Afterbirth Pain
Age Spots
Allergies (respiratory)
Amenorrhea
Anal Fistula or Fissure
Anemia
Appetite (deficient)
Asthma
Autoimmune Disorders
Bronchitis
Canker Sores
Chemotherapy (reducing side effects)
Chicken Pox
Cholera
Chronic Obstructive Pulmonary Disorder
Cirrhosis of the Liver
Cold Sores
Colds (antiviral)
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Colic (adults)
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Colitis
Colon (atonic)
Colon (spastic)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (lymphatic)
Congestion (sinus)
Constipation (adults)
Contagious Diseases
Convalescence
Cough (damp)
Cough (dry)
Cough (general)
Cough (spastic)
Cramps (menstrual)
Crohn's Disease
Croup
Cushing's Disease
Cytomealovirus
Dyspepsia
Eczema
Emphysema
Endometriosis
Enteritis
Epstein Barr Virus
Estrogen (low)
Fatty Liver Disease
Fever
Fibrosis
Gall Bladder (sluggish or removed)
Gall Stones
Gas and Bloating
Gastritis
Gingivitis
Glands (swollen lymph)
Goiter
Gonorrhea
Gout
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Hair (loss or thinning)
Hair Care (general)
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Hangover
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Headache (tension)
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Mononucleosis
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Poison Ivy or Oak
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