Evidence supporting the use of: Omega-3
For the health condition: Allergies (respiratory)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Omega-3 fatty acids, primarily eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been investigated for their potential role in modulating allergic diseases, including respiratory allergies such as allergic rhinitis and asthma. The scientific rationale is based on their anti-inflammatory properties: omega-3s can reduce the synthesis of pro-inflammatory eicosanoids and cytokines, which are implicated in allergic responses. Several observational studies have found correlations between higher omega-3 intake (especially from fish oil) and reduced prevalence or severity of respiratory allergies, particularly in children. Randomized controlled trials (RCTs) in this area, however, have yielded mixed results. Some RCTs report modest improvements in asthma symptoms or markers of airway inflammation with omega-3 supplementation, while others show no significant benefit compared to placebo. Meta-analyses generally conclude that while there is biological plausibility and some supportive evidence, the overall effect size is small and not consistently statistically significant. Professional guidelines do not currently recommend omega-3 supplementation as standard therapy for respiratory allergies, but it may be considered as an adjunct in certain cases. In summary, there is a scientific basis for exploring omega-3s in respiratory allergies, but current evidence is limited and not definitive.

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Products containing Omega-3

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